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ESKAPE Bacteria

Do you wanna play a game?

First things first: This is not about Escape Rooms at any point!

Escape Room

Even though the search for a way out of the impen­ding “anti­bio­tic cri­sis” admit­ted­ly resem­bles a real-life ver­si­on of the tren­dy evening activity.

ESKAPE Gruppe

In fact, ESKAPE is an acro­nym that stands for THE(!) six mul­ti-resistant bac­te­ria against which new medi­ca­ti­ons urgen­tly need to be found.

Eskape bacteria

ESKAPE — a fancy Abbreviation

Even though most of us are unli­kely to remem­ber the names of the­se bac­te­ri­al patho­gens, we should all have heard of them at least once. ESKAPE con­sists of: Ente­ro­coc­cus faeci­um, Sta­phy­lo­coc­cus aureus, Kleb­si­el­la pneu­mo­niae, Aci­n­et­o­bac­ter bau­ma­nii, Pseu­do­mo­nas aeru­gi­no­sa, and Ente­ro­bac­ter spe­ci­es. If you hap­pen to for­get the names, Goog­le will sure­ly be hap­py to assist.

 

Eskape bacteria

So why bother put­ting in the effort to con­den­se six bac­te­ria under a (admit­ted­ly extre­me­ly suc­cessful) acro­nym? Pre­su­ma­b­ly, to stay in the public’s mind. After all, the­se are the very bac­te­ri­al repre­sen­ta­ti­ves against which new anti­bac­te­ri­al sub­s­tances urgen­tly need to be found. Most of us have pro­ba­b­ly heard of the noto­rious hos­pi­tal germs — and the­se six bac­te­ria are among them. In pro­fes­sio­nal cir­cles, they are also often refer­red to as noso­co­mi­al pathogens.

ESKAPE Group — a Hospital phenomenon?

Hos­pi­tal-acqui­red infec­tions have a repu­ta­ti­on for dra­sti­cal­ly exten­ding hos­pi­tal stays. Even with the best and most tho­rough hygie­ne mea­su­res in place, it’s still pos­si­ble to beco­me infec­ted with such a patho­gen. The batt­le against the­se patho­gens now extends to archi­tec­tu­re. In hos­pi­tals, for exam­p­le, atten­ti­on is paid to ensu­ring that faucets, door hand­les, and simi­lar sur­faces have smooth sur­faces and cor­ners are roun­ded rather than sharp. Take a moment to obser­ve this.

 

Eskape Bacteria

Of cour­se, com­ba­ting micro­or­ga­nisms is not as straight­for­ward, and par­ti­cu­lar­ly the repre­sen­ta­ti­ves of the ESKAPE group are excep­tio­nal­ly ten­acious and resistant. They are often the cau­sa­ti­ve agents of see­mingly harm­less infec­tious dise­a­ses. Howe­ver, their mul­ti-resis­tance great­ly limits the­ra­peu­tic opti­ons, dra­sti­cal­ly redu­cing the chan­ces of reco­very. Con­se­quent­ly, Aci­n­et­o­bac­ter bau­ma­nii, for exam­p­le, is now lis­ted by the WHO as one of the bac­te­ria for which new anti­bac­te­ri­al sub­s­tances must urgen­tly be found! Per­haps, howe­ver, the­re has alre­a­dy been suc­cess in this search (see here)?

They just wanna play

Even though the ESKAPE bac­te­ria may not always be dan­ge­rous or harmful to humans and can even cau­se asym­pto­ma­tic infec­tions, it is advi­sa­ble to stay away from all six of them as much as pos­si­ble. They infect almost any­thing that the medi­cal prac­ti­tio­ner can name with fan­cy Latin terms. Espe­ci­al­ly in cases of open wounds, a wea­k­en­ed immu­ne sys­tem, a stay in the inten­si­ve care unit, or recent anti­bio­tic the­ra­py, one is more sus­cep­ti­ble to infec­tion with such a patho­gen. It’s cru­cial to adhe­re clo­se­ly to hygie­ne rules and avo­id cont­act with repre­sen­ta­ti­ves of the ESKAPE group. Social distancing, so to speak.

ESKAPE Bakterien

Tho­se who want to play it safe during a hos­pi­tal stay take precautions…

Social Distancing

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